hrp0092p3-97 | Fat, Metabolism and Obesity | ESPE2019

Metabolic Syndrome in Adults with Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency

Gargouri Imen , Hadjkacem Faten , Safi Wajdi , Ghorbel Dorra , Nabila Rekik , Nadia Charfi , Kamoun Thouraya , Mnif Mouna , Abid Mohamed

Introduction: 21-Hydroxylase deficiency is the most frequent form of congenital adrenal hyperplasia (CAH) which is a common autosomal recessive disorder characterized by impaired adrenocortical and adrenomedullary function, and adrenal hyperandrogenism. Chronic glucocorticoid therapy and excess androgen exposure in patients with CAH may predispose them to developing a metabolic syndrome in adulthood.Our objective is to evaluate the metabolic syndrome in adulth...

hrp0092p3-170 | Growth and Syndromes (to include Turner Syndrome) | ESPE2019

Reevaluation of Congenital Growth Hormone Deficiency in Adulthood

Gargouri Imen , Hadjkacem Faten , Safi Wajdi , Ghorbel Dorra , Kmiha Sana , Nadia Charfi , Rekik Nabila , Mnif Mouna , Hachicha Mongia , Kamoun Thouraya , Abid Mohamed

Introduction: Congenital growth hormone deficiency (GHD) is a non-exceptional cause of short stature. The objective of our study is to re-evaluate the clinical, biochemical, and evolutive features of congenital GHD in Tunisian south in adulthood.Subjects/Methods: We underwent a retrospective study of 48 patients over 16 years old affected by GHD over 28 years (1990- 2018).Resultats...